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P1‐438: NEUROPSYCHIATRIC BURDEN IS RELATED TO INCREASED AMYLOID BUT NOT TAU DEPOSITION IN LATE‐MIDDLE‐ AGED COGNITIVELY NORMAL INDIVIDUALS WITH A FAMILY HISTORY OF ALZHEIMER'S DISEASE
Author(s) -
Binette Alexa Pichet,
Vachon-Presseau Etienne,
Gonneaud Julie,
Marchant Natalie L.,
Bellec Pierre,
Breitner John C.S.,
Villeneuve Sylvia
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.447
Subject(s) - psychology , dementia , neuroticism , personality , cognition , anxiety , clinical psychology , disease , developmental psychology , psychiatry , medicine , social psychology
variable related to Ab burden. 1A. Loading of each neuropsychiatric factor (NPF) and personality trait to the neuropsychiatric latent variable related with Ab accumulation. Confidence intervals are derived from bootstrap resampling. 1B. Cortical regions showing higher Ab SUVR as NPF/personality burden increases. The importance of each region in the model was identified from bootstrap ratios and projected on a brain template. Poster Presentations: Sunday, July 22, 2018 P478