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P1‐385: A DYNAMIC MRI OBSERVATION OF PATIENTS WITH AD AND FTLD
Author(s) -
Li Jie,
Mao Chenhui,
Hou Bo,
Feng Feng,
Fan Yong,
Liu Caiyan,
Dong Liling,
Huang Xinying,
Lei Dan,
Gao Jing
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.393
Subject(s) - temporal lobe , frontal lobe , anatomy , parahippocampal gyrus , medicine , white matter , psychology , neuroscience , magnetic resonance imaging , radiology , epilepsy
in the MTG [r(10)1⁄4-.604, p1⁄4.032], whereas verbal fluency impairment was predicted by Flortaucipir signal in the IFG [r(7)1⁄4-.702, p1⁄4.039]. All results remained similar when the analysis was repeated without partial volume correction and in the right hemisphere. Conclusions:Our results suggest that Flortaucipir imaging is useful for distinguishing between PPA patients with and without Alzheimer’s pathology; and that Flortaucipir signal in PPA patients without Alzheimer’s pathology is behaviorally relevant.