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P1‐301: CERTAIN PLASMA N‐TERMINAL TAU FRAGMENTS ARE ELEVATED IN AD AND AD‐MCI COMPARED TO CONTROLS
Author(s) -
Keshavan Ashvini,
Mengel David,
Chen Zhicheng,
Patel Purvish P.,
Billinton Andy,
Perkinton Michael,
Percival-Alwyn Jennifer L.,
Zetterberg Henrik,
Johnson Keith A.,
Properzi Michael,
Schultz Aaron P.,
Sperling Reisa A.,
Rissman Robert A.,
Galasko Doug R.,
Schott Jonathan M.,
Walsh Dominic M.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.308
Subject(s) - biomarker , cognitive impairment , dementia , medicine , receiver operating characteristic , cohort , immunoassay , oncology , alzheimer's disease , gastroenterology , disease , immunology , chemistry , biochemistry , antibody
Gender (femal Age (years) MMSE CSF Ab42 (pg CSF Tau (pg/m CSF Tau/Ab42 FRAGMENTS ARE ELEVATED IN AD AND AD-MCI COMPARED TO CONTROLS Ashvini Keshavan, David Mengel, Zhicheng Chen, Purvish P. Patel, Andy Billinton, Michael Perkinton, Jennifer L. Percival-Alwyn, Henrik Zetterberg, Keith A. Johnson, Michael Properzi, Aaron P. Schultz, Reisa A. Sperling, Robert A. Rissman, Doug R. Galasko, Jonathan M. Schott, Dominic M. Walsh, Dementia Research Centre, Institute of Neurology, University College London, London, United Kingdom; Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Boston, MA, USA; Centre for Neurologic Diseases, Brigham and Women’s Hospital, Boston, MA, USA; Quanterix Corporation, Cambridge, MA, USA; AstraZeneca, Cambridge, United Kingdom; MedImmune, Cambridge, United Kingdom; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, M€olndal, Sweden; UCL Institute of Neurology, Department of Molecular Neuroscience, University College London, Queen Square, London, United Kingdom; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Center for Alzheimer Research and Treatment, Brigham and Women’s Hospital, Boston, MA, USA; University of California San Diego, La Jolla, CA, USA; Ann Romney Centre for Neurologic Diseases, Brigham and Women’s Hospital, Boston, MA, USA. Contact e-mail: a.keshavan@ucl.ac.uk