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O3‐06‐04: THE MOUSEAC PROJECT: A GENOMEWIDE EXPRESSION ANALYSIS OF MURINE MODELS OF DEMENTIA ACCORDING TO AGE AND BRAIN REGION SIGNIFIES THE IMPORTANCE OF MICROGLIAL PATHWAYS
Author(s) -
Hardy John,
Bayram Sevinc,
Guelfi Manuel S.,
Matarin Maria,
Edwards Frances A.,
Salih Dervis
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2803
Subject(s) - trem2 , transcriptome , biology , genome wide association study , computational biology , gene , disease , genetics , gene expression , microarray , microarray analysis techniques , dementia , rna seq , immune system , single nucleotide polymorphism , medicine , genotype , pathology , myeloid cells
Figure 1. Ancestry percentage of ADNI participants who self-identified as ’non-Hispanic White’ (a) and subjects who have African ancestry >10% (b). John Hardy, Sevinc Bayram, Manuel S. Guelfi, Maria Matarin, Frances A. Edwards, Dervis Salih, University College London, London, United Kingdom; Hitachi Rail Europe, London, United Kingdom; University College London Institute of Neurology, London, United Kingdom; University College London, London, United Kingdom. Contact e-mail: j.hardy@ucl.ac.uk