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P4‐121: DIFFERENCES IN SEMANTIC FEATURE PRODUCTION BETWEEN HEALTHY OLDER AND YOUNG ADULTS
Author(s) -
Vivas Leticia,
Martínez Sandra,
Piccolo Brenda,
García-Coni Ana,
Comesaña Ana,
Vivas Jorge
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2525
Subject(s) - introspection , referent , feature (linguistics) , psychology , normative , age groups , developmental psychology , cognitive psychology , linguistics , demography , philosophy , epistemology , sociology
High Risk and LowAverage/poorMemory class were at an elevated risk of developing incident dementia (HR 1⁄4 13.6, 95%CI 1⁄4 5.9 -31.2 and HR 1⁄4 5.8, 95%CI 1⁄4 2.6 – 12.8) and incident AD (HR 1⁄4 11.1, 95%CI 1⁄4 4.7 – 25.9, and HR 1⁄4 5.0, 95%CI 1⁄4 2.2 – 11.2) in the first four years from baseline assessment, while participants in the Dysexecutive Function class were at an elevated risk for incident all-cause dementia and incident AD after four years of follow-up (HR 1⁄4 6.0, 95%CI 1⁄4 2.5 – 14.3, and HR 1⁄4 7.1, 95%CI 1⁄4 2.7 – 18.4). Results in the Elite class were not applicable in the first 4 years since therewere no cases and, after 4 years results were not significant (there were only 5 cases in total). Conclusions: This study highlights the clinical applicability of the association between a patient’s cognitive profile and future risk of all-cause dementia and AD. This area of research may lead to personalized risk profiles.