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P4‐029: ASSESSING COGNITION USING DUAL‐TASK MOTOR FUNCTION: THE INFLUENCE OF COGNITIVE TASK TYPE
Author(s) -
Ehsani Hossein,
Gomez Tirambulo Coco Victoria,
Mills Caroline Sutherland,
Zamrini Ed,
Mohler Jane,
Toosizadeh Nima
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2431
Subject(s) - montreal cognitive assessment , cognition , receiver operating characteristic , audiology , psychology , task (project management) , physical medicine and rehabilitation , medicine , cognitive impairment , neuroscience , management , economics
reduced alpha for high scores. Similar results were obtained the FCSRT (words), DMS48 (images) and Rey-Osterrieth (complex drawing) memory exams. APOE e4 carriers, and low-job-responsibility workers exhibited higher alpha1 power. Conclusions: These findings indicate that amyloidosis may be associated with two distinct phases. The initial phase of amyloid positivity is related to boosted alpha oscillations, especially in prefrontal areas, which may allow preserving a high level of cognitive performance, until the further increasing amyloidosis breaks down this performancereserving compensatory mechanism and transitions into the classical biomarkerand clinical manifestations of AD pathology.