Premium
IC‐P‐206: QUANTITATIVE SCORING OF [18F] FLORTAUCIPIR PET SCANS IN TYPICAL AND ATYPICAL PHENOTYPES OF ALZHEIMER'S DISEASE
Author(s) -
Makaretz Sara J.,
Collins Jessica A.,
Sweeney Kristin K.,
Krivensky Samantha,
McGinnis Scott M.,
Schultz Aaron P.,
Johnson Keith A.,
Dickerson Brad C.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2273
Subject(s) - primary progressive aphasia , voxel , nuclear medicine , atrophy , medicine , alzheimer's disease , dementia , psychology , disease , radiology , frontotemporal dementia
Figure 2. Voxel-wise mean tau z-score maps relative to young healthy controls are represented for A) amyloid negative CDR 0 older participants, B) amyloid positive CDR 0 participants, and C) amyloid positive CDR > 0 subjects. Results were mapped onto the cortical surface. Z-score of 1.96 represents a statistically significant (p<0.05) difference from controls. Voxel-wise frequency of abnormality maps relative to young healthy controls are represented for D) amyloid negative CDR 0 older participants, E) amyloid positive CDR 0 participants, and F) amyloid positive CDR > 0 subjects. Frequency of abnormality represents the voxel-wise percentage of participants who are abnormal relative to young healthy controls. Sara J. Makaretz, Jessica A. Collins, Kristin K. Sweeney, Samantha Krivensky, Scott M. McGinnis, Aaron P. Schultz, Keith A. Johnson, Brad C. Dickerson, Massachusetts General Hospital, Charlestown, MA, USA; Harvard Medical School, Boston, MA, USA; Brigham and Women’s Hospital, Boston, MA, USA. Contact e-mail: SMAKARETZ@mgh.harvard.edu