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IC‐P‐143: THE DIRECT AND RISK‐MODERATION EFFECT OF MIDLIFE LIFESTYLE ACTIVITIES ON ALZHEIMER'S DISEASE BIOMARKERS
Author(s) -
Jeon So Yeon,
Byun Min Soo,
Yi Dahyun,
Lee Jun Ho,
Choe Young Min,
Ko Kang,
Kim Woo Jin,
Sohn Bo Kyung,
Choi Hyo Jung,
Lee Jun-Young,
Han Myeong-Il,
Lee Dong Young
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2209
Subject(s) - psychology , alzheimer's disease neuroimaging initiative , moderated mediation , mediation , neuroimaging , dementia , apolipoprotein e , medicine , moderation , cognitive decline , magnetic resonance imaging , alzheimer's disease , disease , oncology , gerontology , neuroscience , social psychology , political science , law , radiology
igure 2. Results of moderated mediation model. (A) CA moderated relaonship between APOE4 and HV. (B) PA had significant direct effect on Mglu. Only significant interaction and moderating path were included ut are not shown here for display simplicity. APOE4: Apolipoprotein E 4; CA: Cognitive activity; HV: Hippocampal volume; PA: Physical activy; CMglu: Cerebral glucose metabolism Poster Presentations: Saturday, July 21, 2018 P120