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IC‐P‐060: REGIONAL AND MORPHOLOGICAL CHARACTERISTICS OF ENLARGED PERIVASCULAR SPACES IN RELATIONSHIP TO AMYLOID PET AND CSF Aβ IN ADNI DATASETS
Author(s) -
Boespflug Erin L.,
Schwartz Daniel,
Lahna David,
Silbert Lisa C.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2125
Subject(s) - voxel , white matter , perivascular space , amyloid (mycology) , occipital lobe , pathology , neuroimaging , magnetic resonance imaging , partial volume , neuroscience , anatomy , nuclear medicine , chemistry , psychology , medicine , radiology
separation difficult. While a better subfield separation could be achieved with the low-SNR, high-resolution image (middle column), it did not resolve hippocampal subfields. Because, the low contrast-to-noise ratio imposed a similar artifact to the low-resolution image. Conclusions: The high-SNR, high-resolution image (right column), provided a clear boundary of the layers of the hippocampal subfields.We could image small subregions such as CA3, including the stratum pyramidal of rostral CA3 (yellow arrow), the alveus (blue arrow), and even the endfolial pathway (green arrow). In addition, the SRLM (stratum radiatum lacunosum moleculare) was clearly resolved throughout the hippocampus.