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IC‐P‐024: COMPARISON OF AMYLOID‐β DEPOSITION AND AMYLOID POSITIVITY OF TWO COHORTS USING DIFFERENT QUANTIFICATION METHODS: RESULTS FROM ADNI AND KBASE COHORTS
Author(s) -
Yi Dahyun,
Byun Min Soo,
Lee Jun Ho,
Lee Dong Young
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2088
Subject(s) - cohort , alzheimer's disease neuroimaging initiative , pittsburgh compound b , neuroimaging , nuclear medicine , medicine , psychology , alzheimer's disease , disease , neuroscience
logistic regression model showed that % of abnormal voxels in the lateral temporal lobes was associated with an increased risk of progression to AD dementia at 24-month follow-up (Figure 2). Conclusions: These results support a framework in which the regional distribution of Ab positivity may provide important information regarding the probability of clinical progression from MCI to dementia over a typical 2-year long clinical trial.