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P3‐618: HIGH RED MEAT INTAKE IS ASSOCIATED WITH INCREASED TAU ON [ 18 F]FLORTAUCIPIR PET AND POORER MEMORY
Author(s) -
Risacher Shan L.,
Unverzagt Fred W.,
Apostolova Liana G.,
Clark Daniel,
Farlow Martin R.,
Tallman Eileen F.,
West John D.,
Saykin Andrew J.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1985
Subject(s) - cognition , entorhinal cortex , medicine , temporal lobe , effects of sleep deprivation on cognitive performance , audiology , psychology , hippocampus , neuroscience , epilepsy
adherence defined as a total score>53), cognitive complaints using the ‘Cognitive change index’ self-report (CCI) and depressive symptoms using ‘Center for Epidemiologic Studies Depression Scale’ (CES-D). Using logistic regression analyses, we investigated whether adherence to dietary guidelines was associated with age, sex, education, BMI, MMSE, depressive symptoms or cognitive complaints. Results:90 (54%) of our subjects adhered to the Dutch dietary guidelines. The adhering and non-adhering groups differed at all dietary components, except for fibers (Figure 1). In the non-adherence group, dietary scores were lowest on the components trans fatty acids, saturated fat, salt and fish. Logistic regression analysis showed a relationship between male sex (OR and 95% CI: 0.364 [0.170-0.779]) and more depressive symptoms (CES-D; OR and 95% CI: 0.920 [0.865-0.979]) with less adherence to the dietary guidelines. We found no association between MMSE or cognitive complaints and adherence to dietary guidelines (Table 1). Conclusions: Almost half of the SCD subjects did not adhere to the dietary guidelines. Our findings suggest that the diet of SCD subjects offers room for improvement, mainly in fat, salt and fish consumption, and could be a target for programs aiming to improve brain health.