Premium
P3‐543: ACUTE COGNITIVE EFFECTS OF RESISTANCE BAND PHYSICAL ACTIVITY FOR PEOPLE WITH DEMENTIA
Author(s) -
Elliott-King Jordan A.,
Hogervorst Eef,
Peel Elizabeth
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1908
Subject(s) - dementia , verbal fluency test , cognition , psychology , fluency , clinical psychology , gerontology , medicine , psychiatry , neuropsychology , disease , mathematics education , pathology
dementia (or AD) was not a significant predictor of digoxin concentrations. Conclusions:Dose normalized digoxin concentrations are not different between patients with and without AD, suggesting peripheral P-gp function is likely unaffected in AD. Given P-gp function is reduced at the BBB, additional analyses should be conducted to assess possible alterations in brain disposition of digoxin in patients with AD. Funded by PharmAlliance (RXALL15002), NIH T32GM086330 (I.A) and R35GM122576 (K.L.R.B.).