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P3‐487: THE FRONTOTEMPORAL LOBAR DEGENERATION MODULE (FTLD‐MOD) OF THE UNIFORM DATA SET: PERFORMANCE ON LANGUAGE AND BEHAVIOR MEASURES IN PRIMARY PROGRESSIVE APHASIA (PPA) AND BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA (BVFTD)
Author(s) -
Gefen Tamar,
Teylan Merilee,
Besser Lilah M.,
Weintraub Sandra
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1851
Subject(s) - primary progressive aphasia , frontotemporal dementia , semantic dementia , frontotemporal lobar degeneration , psychology , audiology , boston naming test , dementia , aphasia , fluency , clinical psychology , cognitive psychology , neuropsychology , medicine , disease , cognition , psychiatry , pathology , mathematics education
and white and more recently in color. An important characteristic of this test is that pictures and semantic cues were selected considering psycholinguistic variables from Argentine normative databases. The test is comprised of 30 color images extracted from Cycowicz et al. (1998) set comprising living and non-living things. Psychometric properties of the new color version (PAPDIC) were analyzed. Methods: Clinical sample: 28 patients (18 left brain focal damaged and 10 with neurodegenerative disease). Normative sample paired in age and educational level: 26 subjects without neurological impairment. Subjects were administered a neuropsychological assessment battery including language and semantic memory tests. Psychometric analysis performed: internal consistency was assessed through Kuder-Richardson (KR20) as items were dichotomic; concurrent validity with Spearman s Rho with the brief version of the Boston Naming Test; criteria validity through group comparison (clinical vs control) with Mann-Whitney U test; sensitivity and specificity to detect anomia through ROC curves; and the discriminating power of items through point-biserial correlations with the total test score. Results:The PAPDIC showed a highly acceptable internal consistency value (.927) and a significant correlation with the Boston Naming Test (Spearman s Rho1⁄4 .789; p< .001). Significant group differences were observed (z 1⁄4 -5.242; p < .001). ROC curve analysis showed a Sensitivity of 90% and a Specificity of 100% with an Area Under de Curve of .984 (IC 95% .949-1). The suggested cutting point according to Youden Index was 26. Regarding the discriminating power of individual items, it was observed that the following pictures showed the highest point-biserial correlations: envelope (rpb 1⁄4 .844), brooch (rpb 1⁄4 .798), and fishbowl (rpb 1⁄4 .773). Conclusions:The PAPDIC showed internal consistency between items. Evidence of concurrent and criteria validity were obtained. Specificity and Sensibility values were highly acceptable and showed better discriminating value than the B&W version (AUC 1⁄4 .817). A cutting point to detect anomia was established. Items with better discriminating capacity were identified. Results are promissory and suggest that the PAPDIC could be a useful tool to assess naming difficulties.