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P3‐146: FORMATION AND TOXICITY OF TRANSTHYRETIN (TTR) OLIGOMERS IN VITRO AND IN PATIENTS WITH FAMILIAL AMYLOID POLYNEUROPATHY
Author(s) -
Eisele Yvonne S.,
Janssen Maria E.,
Ma Dan,
Nguyen Bianca,
Plate Lars,
Morgan Gareth J.,
Reixach Natalia,
Buxbaum Joel N.,
Wiseman R. Luke,
Lander Gabriel C.,
Kelly Jeffery W.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1503
Subject(s) - transthyretin , amyloid (mycology) , amyloidosis , amyloid disease , polyneuropathy , protein aggregation , chemistry , in vitro , mutant , protein folding , amyloid polyneuropathy , cytotoxicity , cancer research , medicine , disease , biophysics , biochemistry , pathology , biology , amyloid fibril , amyloid β , gene , age of onset