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P3‐079: INVESTIGATING DIAGNOSTIC BIOMARKERS OF COGNITIVE IMPAIRMENT BY UTILIZING VASCULAR AND NEUROGENIC CHANGES IN THE RETINA
Author(s) -
DeBuc Delia Cabrera,
Kostic Maja,
Oropesa Susel,
Somfai Gabor Mark,
Mendoza-Santiesteban Carlos
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1435
Subject(s) - retinal , retina , ophthalmology , central retinal vein , medicine , erg , electroretinography , cardiology , neuroscience , psychology
aMCI vs. SCD (ACC < 67%, AUC < 0.71). Conclusions: Atrophy of memory-related brain structures are replicated across early stages of AD. These changes help machine learning algorithms to accurately identify individuals with SCD and aMCI from NC. Our findings have important implications on development of potential brain imaging marker for early prediction and conversion of AD. P3-079 INVESTIGATING DIAGNOSTIC BIOMARKERS OF COGNITIVE IMPAIRMENT BY UTILIZING VASCULAR AND NEUROGENIC CHANGES IN THE RETINA Delia Cabrera DeBuc, Maja Kostic, Susel Oropesa, Gabor Mark Somfai, Carlos Mendoza-Santiesteban, Bascom Palmer Eye Institute, Miami, FL, USA; Retinology Unit, Pallas Kliniken, Olten, Switzerland; Department of Ophthalmology, Semmelweis University, Budapest, Hungary. Contact e-mail: dcabrera2@med.miami.edu