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P2‐580: TWENTY‐YEAR TRENDS IN PROPORTIONAL MORTALITY IN A PROBABLE AD COHORT
Author(s) -
Pavlik Valory N.,
Darby Eveleen,
Kass Joseph S.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1275
Subject(s) - medicine , dementia , cohort , disease , logistic regression , demography , cohort study , pediatrics , gerontology , sociology
impairment. Many of these contain neurotoxic and carcinogenic properties known to cause cancer, reproductive problems, and central nervous system impairments that have been linked to Alzheimer’s disease. Nail salon technicians are continuously exposed to them, and this exposure may occur at greater frequency and at higher levels than in other occupational settings. This research aims to examine the association of neurotoxin-exposure with mild cognitive impairment among Vietnamese female nail technicians aged 50 or above in the Northern California areas. Methods: Quasi-experimental interviews were conducted with 45 Vietnamese female nail technicians to assess the association between mild cognitive impairment and early dementia (e.g. MOCA) with occupational exposure (e.g. years of employment, work hours per week), demographics (e.g. education, age), depression (e.g. CESD scale) and acculturation level (e.g. US citizenship). Results: Multiple regression analysis revealed that among Vietnamese female nail technicians, level of education (b 1⁄4 1.36, p 1⁄4 0.010) and depression (b 1⁄4 -4.22, p 1⁄4 0.007) significantly predict mild cognitive impairment. Work hours per week (b 1⁄4 2.53, p 1⁄4 0.065) and having US citizenship (b 1⁄4 -3.79, p 1⁄4 0.63) are also marginally significant. Conclusions: Preliminary results from Year 1 show that Vietnamese female nail technicians may be at risk for mild cognitive impairment. Explanations for why working more hours are positively associated with higher MOCA score will be discussed. Research is funded by the Alzheimer’s Association.