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P2‐579: COGNITIVE IMPAIRMENT AND VIETNAMESE FEMALE NAIL TECHNICIANS
Author(s) -
Nguyen Thuc-Nhi,
Ho Janis
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1274
Subject(s) - vietnamese , medicine , dementia , montreal cognitive assessment , nail (fastener) , neuropsychology , cognition , cognitive impairment , clinical psychology , audiology , disease , psychiatry , philosophy , linguistics , materials science , metallurgy
Impairment (MCI). The MoCA has a high sensitivity for detection of MCI in patients who would score as normal on the Mini Mental State Examination, however, its widely established cut-off of 26 for impairment may not be optimal for use in minority populations. Methods: Data come from the National Alzheimer’s Coordinating Center’s (NACC) Uniform Data Set (UDS) for visits conducted until the December 2017 data freeze. Participants who completed a MoCA at their baseline visit and reported being either non-Hispanic white, non-Hispanic black, or Hispanic were included in this analysis (n1⁄43,539). SAS 9.4 was used to calculate descriptive statistics. Results: Of the participants included in this analysis, 69.4 years old on the average, 81.2% were non-Hispanic white, 13.9% were non-Hispanic black, and 4.9% were Hispanic. Most had normal cognition (47.0%), as judged by a clinician, and the average rawMoCA scorewas 22.3. Using the cut-off of 26, the sensitivity of the MoCA was 87.4% in non-Hispanic whites, 94.3% in non-Hispanic blacks, and 93.8% in Hispanics; the specificity of the MoCAwas 73.8% in non-Hispanic whites, 37.3% in non-Hispanic blacks, and 49.4% in Hispanics; the positive predictive value of the MoCAwas 80.0% in non-Hispanic whites, 53.3% in non-Hispanic blacks, and 69.2% in Hispanics. Conclusions: Differences observed may be due to a lack of cultural equivalence of test items or to differential variability inMoCA score by race/ethnicity. The low specificity and positive predictive value of the MoCA observed in nonHispanic blacks and Hispanics highlight a need to further investigate more appropriate cut-offs in minority groups to correctly identify cognitive impairment. Given the diversity if the United States population such norms will become increasingly important.

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