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P2‐570: FEASIBILITY OF VIRTUAL REALITY IN COGNITIVE ENHANCEMENT FOR PERSONS WITH YOUNG ONSET COGNITIVE IMPAIRMENT: A PRELIMINARY STUDY
Author(s) -
Silva Eveline,
Yong Ting Ting,
Kandiah Nagaendran
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1265
Subject(s) - virtual reality , cognition , clarity , psychological intervention , cognitive intervention , psychology , population , medicine , intervention (counseling) , distress , applied psychology , clinical psychology , computer science , psychiatry , human–computer interaction , biochemistry , chemistry , environmental health
Background: Atypical antipsychotics have been highlighted in clinical practice due to ability to promote antipsychotic action at recommended doses without producing extrapyramidal symptoms and better efficacy for positive, negative and cognitive symptoms. Methods: A quantitative and qualitative research was undertaken with 20 neurologists (NEU) and 10 geriatricians (GER) to explore their prescriptive routine over aripiprazole, olanzapine, risperidone and quetiapine, as well as to evaluate indications versus patient profiles for these drugs. Results: The major diseases for which physicians prescribe atypical antipsychotics are: Dementia (35%: NEU; 70%: GER), Alzheimer’s (45%: NEU), Insomnia / sleep disorder (30%; NEU), Depression (70%: GER) and Schizophrenia (40%: GER). With respect to the most appropriate patient profile for each drug: between neurologists and geriatricians, aripiprazole is suitable for: patients with higher purchasing power, who did not respond to previous treatment, treatment of negative symptoms / blunting, mania / hypomania crisis and young patients. Olanzapine is suitable for: patient with normal / lean weight, higher purchasing power, younger, negative symptoms / blunting, failure of previous treatment, with insomnia or sleep disorders. Quetiapine is suitable for: elderly patient, with insomnia / sleep disorders, mild or moderate clinical condition, failure of previous treatment, acute phase of illness and with associated anxiety. In turn, risperidone is suitable for: failure of previous treatment, patient with normal / lean weight, first psychotic episode, elderly patient and with mild or moderate clinical condition. The most commonly prescribed antipsychotics are quetiapine and risperidone and the main reasons are given in Table 1. Conclusions: Physicians use several options of antipsychotics in clinical practice, adapting the treatment to patient profile. The results showed that prescription took in account multiple presentations, easy dosage adjustment, safety related to extrapyramidal effects, action on insomnia and symptoms of agitation and aggressiveness, efficacy in psychotic episodes and dementia.