Premium
P2‐512: INFLUENCE OF GENETIC POLYMORPHISMS ON CHANGE IN COGNITIVE DOMAINS, COGNITIVE IMPAIRMENT AND DEMENTIA: AGE EFFECT? RESULTS FROM A FOUR‐YEAR LONGITUDINAL STUDY IN AN ELDERLY POPULATION (INVECE.AB)
Author(s) -
Vaccaro Roberta,
Poloni Tino Emanuele,
Medici Valentina,
Chikhladze Maia,
Abbondanza Simona,
Zaccaria Daniele,
Davin Annalisa,
Cereda Cristina,
Guaita Antonio
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1206
Subject(s) - dementia , cognitive decline , cognition , single nucleotide polymorphism , longitudinal study , episodic memory , psychology , medicine , population , audiology , gerontology , disease , psychiatry , genetics , biology , pathology , genotype , gene , environmental health
demographics is able to predict Ab+ as clinical utility, suggesting potential surrogate methods for detecting Ab burden non-invasively. More specifically, it would be a very brief screening tool in various settings for recruiting participants with potential biomarker evidence of AD brain pathology, such as prevention trials aimed at finding an anti-amyloid drug effect in non-demented population.