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P2‐495: BEHAVIORAL AND MRI MEASURES SHOW IMPAIRED SPATIAL INHIBITION OF RETURN IN MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE
Author(s) -
Jacobs Jessica,
Shattuck Kyle,
Ashburn Sikoya,
Horton Wesley,
DiBattista Amanda M.,
Rebeck G. William,
Howard James H.,
Turner Raymond Scott,
Jiang Xiong
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.1188
Subject(s) - stimulus (psychology) , audiology , inhibition of return , psychology , analysis of variance , alzheimer's disease , cognition , cognitive impairment , post hoc analysis , disease , neuroscience , developmental psychology , medicine , visual attention , cognitive psychology
from FCSRT alone at 3 (p1⁄40.04), 4 (p1⁄40.05) and 5 years (p1⁄40.02); but not from CRRSTalone (p>0.05). Conclusions:Examining CRRST retrieval speed and level of performance jointly with FCSRT level of performance improved prediction of future cognitive impairment over FCSRT level of performance alone. The addition of speed of performancemay account for the additional variance explained in the prediction models and may be a symptom of underlying brain function leading to early cognitive impairment.