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P1‐054: REVISITING FAILED CLINICAL TRIALS: APPLICATION OF QUANTITATIVE SYSTEMS PHARMACOLOGY TO THE IMPACT OF COMEDICATIONS, GENOTYPES AND AMYLOID STATUS ON SEROTONIN MODULATORS
Author(s) -
Spiros Athan,
Geerts Hugo,
Roberts Patrick
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.056
Subject(s) - donepezil , pharmacology , antidepressant , medicine , neuroscience , major depressive disorder , serotonin , pharmacodynamics , psychology , cognition , dementia , disease , pharmacokinetics , receptor , hippocampus