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P1‐045: ESTROGEN TREATMENT IN YOUNG POSTMENOPAUSAL WOMEN WITH SUBJECTIVE COGNITIVE DECLINE DOES NOT MITIGATE ANTICHOLINERGIC EFFECTS ON COGNITIVE PERFORMANCE
Author(s) -
Conley Alexander C.,
Albert Kimberly,
Kim Shin-Gyeom,
Perlman Caroline,
Julie Dumas,
Newhouse Paul A.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.046
Subject(s) - placebo , estrogen , menopause , effects of sleep deprivation on cognitive performance , cognition , anticholinergic , medicine , psychology , cognitive decline , dementia , cholinergic , psychiatry , disease , alternative medicine , pathology
group (P<0.05). ADAS-cog was significantly lower than that before treatment and control group (P<0.05). After 4 months of treatment, theMMSE of control group was higher than before treatment (P<0.05). After 4 months follow-up, WMS-IV was significantly lower than that before treatment (P<0.05). Conclusions: The moderate-Intensity aerobic exercise can improve the cognitive function, especially memory function in AD patients.