Premium
P1‐017: IMPROVEMENT OF THE PSYCHOLOGICAL PROFILE OF OLDER ADULTS WITH AMNESTIC MILD COGNITIVE IMPAIRMENT (AMCI) BENEFITS SUBJECTIVE, BUT NOT OBJECTIVE, COGNITION
Author(s) -
Larouche Eddy,
Chouinard Anne-Marie,
Morin-Alain Valérie,
Goulet Sonia,
Hudon Carol
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.018
Subject(s) - mindfulness , psychology , psychoeducation , anxiety , mood , cognition , psychological intervention , clinical psychology , repeated measures design , psychiatry , statistics , mathematics
more than placebo (mean difference 1.40; 95%CI 0.56–2.25) and galantamine (mean difference 1.38; 95%CI 0.53–2.23) (Figure 1). In addition, methylphenidate led to better performance on the third trial of the immediate recall of the VVLT-15 compared to placebo (mean difference in recalled words 0.59; 95%CI 0.03–1.15; p1⁄40.04) and galantamine (mean difference 1.11; 95%CI 0.56– 1.67; p<0.001). Galantamine did not improve performance on adaptive tracker or VVLT-15. Conclusions: In this proof of concept trial in patients with VCI, methylphenidate improved tests of executive functioning and immediate recall, whereas galantamine did not.