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[P4–536]: DO DEMOGRAPHIC AND VASCULAR RISK FACTORS PREDICT COGNITIVE CHANGE IN 11,070 UK BIOBANK PARTICIPANTS?
Author(s) -
FawnsRitchie Chloe,
Cox Simon R.,
Richards Marcus,
Gallacher John,
Starr John M.,
Deary Ian J.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.07.698
Subject(s) - cognitive decline , demography , dementia , medicine , cognition , gerontology , cohort , biobank , body mass index , cognitive test , waist , cohort study , psychology , disease , psychiatry , sociology , biology , genetics
was additionally associated with both the ventral attention and limbic networks (p<0.05). Conclusions: Cortical thickness in the limbic network is associated with measures of memory on list-learning tasks of the RAVLTand ADAS-Cog. However, the LMS may be associated with a combination of ventral attention and limbic networks. Since the LMS tests episodic memory, it may recruit multiple brain networks, whereas the list-learning tasks of RAVLT and ADAS-Cog may more strongly engage the limbic network. References Yeo et al., “The organization of the human cerebral cortex estimated by intrinsic functional connectivity,” J Neurophysiol. 2011 Sep; 106(3):1125-1165.