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[P4–484]: BLOOD‐BRAIN BARRIER DYSFUNCTION MAY MEDIATE COGNITIVE IMPAIRMENT DUE TO VASCULAR RISK FACTORS BURDENS
Author(s) -
Lu Dongwei,
Sun Dong,
Zhang Junjian
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.07.645
Subject(s) - cognition , cardiology , medicine , blood–brain barrier , hippocampus , psychology , neuroscience , central nervous system
Beta(13w30Hz), Gamma(30w50Hz). Absolute power is the sum of each EEG power wave. Relative power was calculated as the absolute power of eachwave divided by the sumof absolute power of all waves. Relative power without delta was calculated as the absolute power of each wave divided by the sum of absolute power of the rest waves excepting for delta. Results:Alpha wave showed the striking results among all waves. Alpha absolute power in AD decreased compared to control group. (Figure 1.A)The relative power and the relative power without delta waves in AD decreased compared to the control group (Figure 1.B, C), which has shown similiar to other studies. The alpha power’s gap between AD patients and controls showed the clear distinction in the relative powerwithout delta. Themost effective result was obtained from relative power without delta. Conclusions:Variance of delta had most influence on the result. Even though obtaining EEG was difficult due to delta signal, we showed the possibility that dementia could be diagnosed by measuring EEG signals, especially using relative power of brain waves without delta. This study was supported by 2016 Fund of Chungnam National University.