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[O4–01–04]: COGNITIVE FUNCTIONING AND DECLINE IN TYPE 2 DIABETES: EVIDENCE SUPPORTING A BROAD COGNITIVE ASSESSMENT AT THE EARLIER STAGES OF T2D
Author(s) -
Beeri Michal Schnaider,
Ganmore Ithamar
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.07.420
Subject(s) - prediabetes , cognition , type 2 diabetes , effects of sleep deprivation on cognitive performance , cognitive decline , medicine , cognitive skill , psychology , gerontology , diabetes mellitus , disease , psychiatry , dementia , endocrinology
Never abusers had significantly higher NPI-Q scores and more items endorsed than remote abusers for each CDR stage, except CDR1⁄43 which had a small N(Never Abusers N1⁄41040 vs. Any Abuse N1⁄474). CDR-SB did not differ significantly between Never Abusers and those with history of abuse. Conclusions: Our results associate alcohol abuse with increased and more severe NPI-Q behavioral symptoms. Remote abusers exhibit more symptoms than never-abusers, supporting the hypothesis that alcohol abuse is associated with long-lasting behavioral symptoms. However, Alcohol abuse history does not appear to change functional socres based on CDR-SB. The NACC database is funded by NIA/NIH Grant U01 AG016976.