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[P2–333]: CAVEATS WHEN SUBTRACTING TWO SERIAL MEASUREMENTS TO ESTIMATE THE NUMBER OF PARTICIPANTS NEEDED FOR CLINICAL TRIALS THAT ARE LONGER OR SHORTER THAN THE OBSERVED MEASUREMENT INTERVAL
Author(s) -
Chen Kewei,
Xiong Chengjie,
Harvey Danielle,
Guo Xiaojuan,
Weiner Michael,
Jagust William J.,
Reiman Eric M.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.987
Subject(s) - subtraction , statistics , sample size determination , mathematics , standard deviation , confidence interval , randomized controlled trial , interval (graph theory) , type i and type ii errors , multiplier (economics) , medicine , statistical power , arithmetic , combinatorics , economics , macroeconomics
P2-333 CAVEATS WHEN SUBTRACTING TWO SERIAL MEASUREMENTS TO ESTIMATE THE NUMBEROF PARTICIPANTS NEEDED FOR CLINICAL TRIALS THATARE LONGER OR SHORTER THAN THE OBSERVED MEASUREMENT INTERVAL Kewei Chen, Chengjie Xiong, Danielle Harvey, Xiaojuan Guo, Michael Weiner, William J. Jagust, Eric M. Reiman, Banner Alzheimer’s Institute, Phoenix, AZ, USA; University of Arizona, Tucson, AZ, USA; Arizona State University, Tempe, AZ, USA; Arizona Alzheimer’s Consortium, Phoenix, AZ, USA; Knight Alzheimer’s Disease Research Center, St. Louis, MO, USA; Washington University in St. Louis School of Medicine, St. Louis, MO, USA; University of California, Davis, CA, USA; Beijing Normal University, Beijing, China; Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Administration Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA; Lawrence Berkeley National Laboratory, Berkeley, CA, USA; University of California Berkeley, Berkeley, CA, USA; Translational Genomics Research Institute, Phoenix, AZ, USA. Contact e-mail: kewei.chen@bannerhealth.com