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[P2–307]: INTERMEDIATE CHANGES IN COGNITION PREDICT LONG TERM OUTCOMES IN MILD ALZHEIMER's DISEASE DEMENTIA
Author(s) -
Reed Catherine C.,
Lebrec Jeremie,
Jones Roy W.,
Bruno Giuseppe,
Dell'Agnello Grazia,
Monkul E. Serap,
Andrews Jeffrey Scott
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.961
Subject(s) - dementia , institutionalisation , hazard ratio , medicine , cohort , cognitive decline , disease , proportional hazards model , cohort study , cognition , prospective cohort study , gerontology , alzheimer's disease , pediatrics , psychiatry , confidence interval
Cronbach’s alpha. Results:Unidimensionality was supported by CFA and EFA tests (CFI1⁄40.992, TLI1⁄40.990, first factor at 73% and a ratio of 24.33) after the removal of 6 items. The 10-item scale (FIELDS, OCCUP, MARKET, FESTI, CEREMONI, FINANCES, MOVE, HOME, MEAL and LAUNDRY) fit the IRT model, showed a good coverage of the CA-D scale (threshold parameters range: -2.56 to 3.82) with good item discrimination properties (discrimination item parameters: 1.40 to 4.08) and a high reliability (Cronbach’s alpha1⁄40.92). No DIF were found due to gender, age, education level or cognitive status, but the analyses showed DIF for geographical purposes (country) with an effect of rural and urban environment. Conclusions: These results provide good support for the reliability and internal validity of the CA-D scale as a promising tool for dependency assessment in the elderly population in the diagnosis of dementia in Central Africa context. Further research need to investigate the scale external validity and scale calibration to ensure its generalizability in African studies.