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[P2–256]: EARLY ONSET ALZHEIMER's DISEASE PATIENT WITH AMYLOID PRECURSOR PROTEIN (V669L) MUTATION
Author(s) -
Kang Min Ju,
Han MoonKu
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.908
Subject(s) - psen1 , presenilin , atrophy , psychology , early onset alzheimer's disease , temporal lobe , amyloid precursor protein , medicine , hippocampal formation , alzheimer's disease , neuroscience , pathology , disease , epilepsy
29+/-1.41) were enrolled and provided samples. AD subjects were significantly older and more impaired on the MMSE compared to NC. The saliva Ab42 levels were significantly higher in AD than in NC (53.95+/-7.41 vs 20.63+/-0.72, p<0001). Conclusions:We report results of a simple, non-invasive test to potentially be used as an adjunct to diagnose Alzheimer’s disease (AD). We will report a larger sample size. Future studies will assess the accuracy of the test in MCI and PD and other conditions.