Premium
[P2–073]: INTRANASAL ADMINISTRATION OF INSULIN PREVENTS ANESTHESIA‐INDUCED COGNITIVE IMPAIRMENT AND CHRONIC NEUROBEHAVIORAL CHANGES
Author(s) -
Gong ChengXin,
Chen Yanxing,
Dai Chunling,
Wu Zhe,
Iqbal Khalid,
Liu Fei
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.722
Subject(s) - morris water navigation task , anesthesia , sevoflurane , fear conditioning , medicine , nasal administration , open field , barnes maze , propofol , inhalation , spatial learning , cognition , pharmacology , amygdala , psychiatry
Ongoing Task Performance: Accuracy 1.83** .27 1.34* .20 1.23* .18 Ongoing Task Performance: Speed .01*** .40 .01*** .35 .01*** .35 Cognitive Ability: Attention .01 .01 .23 .01 Cognitive Ability: Memory .84 .14 .79 .13 Cognitive Ability: Fluency 1.53** .24 1.56** .24 Cognitive Ability: Language -1.71 -.15 -1.41 -.13 Cognitive Ability: Visuospatial Skills .47 .07 .67 .10 Self-reported Cognitive Inefficiency -1.35* -.173 R .23 .32 .34 F 18.42*** 8.06*** 7.91*** DR .23 .09 .03 DF 18.42*** 3.26** 5.02*