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[P1–566]: IS THERE AN ASSOCIATION BETWEEN CANCER AND DEMENTIA IN COHORTS WITH AND WITHOUT T2DM? A NATIONAL OBSERVATIONAL STUDY
Author(s) -
Bassil Darina,
Muller David,
UdehMomoh Chinedu T.,
Tzoulaki Ioanna,
Middleton Lefkos T.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.582
Subject(s) - medicine , cancer , hazard ratio , incidence (geometry) , dementia , prediabetes , observational study , type 2 diabetes mellitus , cohort study , demography , type 2 diabetes , oncology , diabetes mellitus , disease , confidence interval , endocrinology , physics , sociology , optics
vs. 87.5 per 100 person-years). Number of planned admissions didn’t differ between the dementia subtypes, but DLB patients had more frequent of emergency admissions. We detected a strong association between DLB and hospitalization, which remained significant after adjusting for a wide range of confounders (hazard ratio: 1.59; 95% CI: 1.19-2.13). DLB patients had more admissions due to Parkinsonian symptoms, atrial fibrillation, constipation and delirium. Conclusions: DLB patients are more frequently admitted to hospital as emergencies and utilize inpatient care to a substantially higher degree than AD patients or the general older population. It would be important to assess whether hospitalizations can be reduced by identifying DLB earlier and providing more targeted outpatient care.