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[P1–411]: WHITE MATTER HYPERINTENSITIES AND VASCULAR RISK FACTORS IN COGNITIVELY HEALTHY ELDERLY MONOZYGOTIC TWIN PAIRS
Author(s) -
Kate Mara ten,
Sudre Carole H.,
Braber Anouk,
Konijnenberg Elles,
Cardoso M. Jorge,
Scheltens Philip,
Ourselin Sebastien,
Boomsma Dorret I.,
Barkhof Frederik,
Visser Pieter Jelle
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.427
Subject(s) - monozygotic twin , twin study , hyperintensity , correlation , cardiology , framingham heart study , framingham risk score , medicine , biology , heritability , genetics , mathematics , magnetic resonance imaging , disease , radiology , geometry
Figure 2. Similarity of WMH distribution across regions. Histograms of WMH correlations across regions in true twin pairs and in random pairs. The WMH data was centered per region prior to computing the within pair correlation across regions. Mara ten Kate, Carole H. Sudre, Anouk den Braber, Elles Konijnenberg, M. Jorge Cardoso, Philip Scheltens, Sebastien Ourselin, Dorret I. Boomsma, Frederik Barkhof, Pieter Jelle Visser, Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands; Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom; Department of Biological Psychology, VU University, Amsterdam, Netherlands; Translational ImagingGroup, Centre for Medical Image Computing, University College London, London, United Kingdom; Centre for Medical Image Computing, University College London, London, United Kingdom; Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, Netherlands; School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands; Alzheimer Center and Department of Neurology, Amsterdam Neuroscience Campus, VU University Medical Center, Amsterdam, Netherlands. Contact e-mail: m.tenkate1@vumc.nl