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[P1–398]: TAU ACCUMULATION IS DETECTABLE AND CORRELATED TO AMYLOID BURDEN IN NORMAL AND IMPAIRED OLDER INDIVIDUALS USING SERIAL PET
Author(s) -
Johnson Keith,
Cosio Danielle M.,
Becker Alex,
Schultz Aaron P.,
Lee Chris,
Andrea Nick,
Hanseeuw Bernard J.,
Sperling Reisa A.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.414
Subject(s) - nuclear medicine , cohort , positron emission tomography , pittsburgh compound b , cognitive impairment , medicine , alzheimer's disease , white matter , cardiology , psychology , pathology , magnetic resonance imaging , disease , radiology
Figure 1. cSUVR by ROI, amyloid burden, and subgroup * Denotes p<0.05 in independent sample t-tests for group comparisons between MCI/AD and all CN group means (upper level) or between high-PiB and low-PiB group means (lower level). Grey COVs are for all CN and MCI/AD groups; COVs for highand lowPiB CN groups are given according to the figure legend. Nonzero mean single-sample t-test p value levels: p>0.05, 0.001