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[P1–376]: DIAGNOSTIC UTILITY OF FDG‐PET IN DIFFERENTIATING ALZHEIMER's DISEASE FROM FRONTO‐TEMPORAL LOBAR DEGENERATION
Author(s) -
Boccardi Marina,
Altomare Daniele,
Festari Cristina,
Rivolta Jasmine,
Gandolfo Federica,
Orini Stefania,
Bouwman Femke H.,
Frisoni Giovanni B.,
Nobili Flavio
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.392
Subject(s) - gold standard (test) , medicine , neuropsychology , critical appraisal , medline , positron emission tomography , pathology , nuclear medicine , psychiatry , cognition , alternative medicine , political science , law
data from individuals with subjective memory complaints, Alzheimer’s disease, dementia with Lewy bodies, frontotemporal dementia and vascular dementia, and provides an index measuring the similarity of data from each individual to these specific etiologies. Results:Demographics of the cohort are presented in Table 1. Table 2 shows the distribution of clinical baseline diagnoses without and with the PredictND tool. Our results show that the syndrome diagnosis (dementia/MCI/healthy) was changed in 4 % of cases and the etiological diagnosis in 23 % of cases. Final analyses on the diagnostic accuracy will be performed after the “gold standard diagnosis” from the ongoing 12-month follow-ups become available. Conclusions:Our preliminary results from comprehensive baseline information indicate that especially etiology diagnosis is challenging and influenced by the tool. Comprehensive analysis on the added-value of the tool will be made when the reference diagnoses are available.