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[P1–370]: AGE‐RELATED DIFFERENCES IN THE MODULATION OF RESTING‐STATE FUNCTIONAL CONNECTIVITY FOLLOWING REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION
Author(s) -
AbellanedaPerez Kilian,
VaquéAlcázar Lídia,
Solana Elisabeth,
VidalPiñeiro Didac,
Bargallo Núria,
PascualLeone Alvaro,
BartrésFaz David
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.386
Subject(s) - transcranial magnetic stimulation , resting state fmri , default mode network , stimulation , neuroscience , psychology , functional connectivity , cognition , prefrontal cortex , brain stimulation , cognitive decline , medicine , disease , dementia
anxiety, blessed dementia scale-activities of daily living and history of hypertension for group C; raw scores of word list recall and recognition, and constructional recall for group N; triiodothyronine, high-density lipoprotein cholesterol, erythrocyte sedimentation rate, and APOE 4 positivity for group L; adjusted hippocampal volume for group I. In the ROC analyses, AUC for the prediction models were as follows: 0.793 for group C, 0.894 for combined group C+N, 0.956 for combined group C+N+L, and 0.944 for combined group C+N+L+I. Conclusions:The findings suggest that the systematic combinations of data obtained from routine clinical practice may be successfully used to predict Ab positivity in MCI individuals.