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[P1–187]: NOVEL METHOD FOR OLIGOMERIC Aβ DETECTION REVEALS INTRACELLULAR ACCUMULATION OF Aβ UPON LOW‐DOSE TREATMENT WITH A GAMMA‐SECRETASE INHIBITOR
Author(s) -
Agholme Lotta,
Clarin Marcus,
Gkanatsiou Eleni,
Kettunen Petronella,
Brinkmalm Gunnar,
Blennow Kaj,
Bergström Petra,
Portelius Erik,
Zetterberg Henrik
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.254
Subject(s) - intracellular , in vitro , chemistry , antibody , microbiology and biotechnology , biochemistry , pharmacology , medicine , biology , immunology
P1-187 NOVEL METHOD FOR OLIGOMERIC Ab DETECTION REVEALS INTRACELLULAR ACCUMULATION OFAb UPON LOW-DOSE TREATMENT WITH A GAMMASECRETASE INHIBITOR Lotta Agholme, Marcus Clarin, Eleni Gkanatsiou, Petronella Kettunen, Gunnar Brinkmalm, Kaj Blennow, Petra Bergstr€om, Erik Portelius, Henrik Zetterberg, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, M€olndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, M€olndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, M€olndal, Sweden; University College London, Institute of Neurology, London, United Kingdom. Contact e-mail: lotta.agholme@neuro.gu.se