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[P1–176]: NEPRILYSIN IS THE MAJOR ENZYME TO DEGRADE EXTRACELLULAR Aβ IN NOVEL AD ANIMAL MODELS
Author(s) -
Sasaguri Hiroki,
Sekiguchi Misaki,
Matsuba Yukio,
Saito Takashi,
Saido Takaomi C.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.243
Subject(s) - neprilysin , extracellular , insulin degrading enzyme , in vivo , downregulation and upregulation , knockout mouse , enzyme , chemistry , presenilin , intracellular , genetically modified mouse , endocrinology , medicine , biology , transgene , alzheimer's disease , biochemistry , disease , gene , microbiology and biotechnology