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[P4–179]: ASPECTS OF SUBJECTIVE COGNITIVE DECLINE THAT PREDICT INCIDENT MCI IN THE MAYO CLINC STUDY OF AGING
Author(s) -
Corien van Harten Argonde,
Hagen Clinton E.,
Edwards Kelly,
Mielke Michelle M.,
SwensonDravis Dana,
Knopman David S.,
Roberts Rosebud O.,
Geda Yonas E.,
Petersen Ronald C.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.2046
Subject(s) - cognition , cognitive decline , population , anxiety , hazard ratio , psychology , depression (economics) , medicine , effects of sleep deprivation on cognitive performance , clinical psychology , disease , audiology , gerontology , psychiatry , dementia , confidence interval , environmental health , economics , macroeconomics
to perform a cross-cultural adaptation of a Brazilian version of Cognitive Function Instrument (CFI). It is an instrument developed by the Alzheimer’s Disease Cooperative Study Group for evaluation of Subjective Cognitive Decline. The project consisted of a cross-sectional study where the original instrument in English was translated and adapted into the Portuguese language. The sample consisted of individuals recruited from among the patients’ caregiver from the Cognitive Neurology outpatient clinic of the Medical School of University of S~ao Paulo.Results:This transcultural translation and adaptation process consisted of six stages: initial translation by two translators, synthesis, back translation by two others translators, review by a committee of experts and pretesting of a draft. The preliminary version was applied in 37 individuals. The mean age was 63.5 years with an average of 10.4 years of schooling. In final review, decisions taken by the committee of experts sought to obtain semantic, idiomatic, experimental and conceptual equivalence between the source and the translated version. Throughout the process, all problems found were solved to ensure the quality of the instrument and its appropriateness to the target population. Conclusions:We elaborated a translated and adapted version of an instrument that can be applied to evaluate Subjective Cognitive Decline in the Brazilian population. This instrument is being validated in a cohort of normal elderly without and with subjective cognitive decline and compared with biomarkers of Alzheimer’s disease.