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[P3–563]: RISK FACTORS FOR DEMENTIA AND COGNITIVE FUNCTION IN HEALTHY ADULTS
Author(s) -
Huntley Jonathan D.,
Corbett Anne,
Wesnes Keith,
Hampshire Adam,
Ballard Clive
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1783
Subject(s) - dementia , cognition , effects of sleep deprivation on cognitive performance , psychology , depression (economics) , gerontology , working memory , clinical psychology , cognitive decline , psychological intervention , medicine , psychiatry , disease , pathology , economics , macroeconomics
the Down Syndrome Registry shows that individuals with DS and AD have a higher prevalence of metabolic risk factors. Since these risk factors are modifiable, and their aggressive management and reversal have shown to reduce the pathophysiological markers of AD in non-DS populations, future studies are needed to investigate the association between metabolic and vascular risk factors and AD among the DS population, and explore mechanisms of prevention of cognitive impairment by management of these factors.