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[P3–293]: COGNITIVE IMPAIRMENT, INSOMNIA AND QUALITY OF LIFE IN A SAMPLE OF OLD PEOPLE IN MEXICO
Author(s) -
GuerreroCantera José
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1507
Subject(s) - insomnia , dementia , quality of life (healthcare) , depression (economics) , cognition , medicine , cognitive impairment , clinical psychology , psychiatry , gerontology , psychology , disease , nursing , economics , macroeconomics
We tested this hypothesis in two birth cohorts on reaching age about 65 years some 18 years apart. Cohorts were born 1930-1932 (C30) or 1950-1952 (C50) and followed up from 1993 up to 2016 in our Interdisciplinary Longitudinal Study of Adult Development and Ageing (ILSE). Methods: ILSE cohorts underwent medical and neuropsychological assessments. We contrasted prevalence of MCI and Mild Cognitive Disorder attributable to medical conditions (MCD) between C30 at the second examination (1998, n1⁄4 222; mean age: 66.5) and C50 at the fourth examination (2016, n1⁄4166; mean age: 63.6). The effect of diagnoses of MCI/MCD on attention, memory, psychomotor speed/mental flexibility, visuo-spatial and abstract thinking was investigated using ANOVAs. Results: 25.23% of C30 met criteria for MCI in 1998, while 9.64% of C50 were diagnosed with MCI in 2016. Moreover, 12.16% of C30 were diagnosed with MCD at the second examination wave in contrast to 7.83% of C 50 at the fourth examination wave. Chi-Square analysis was significant with c1⁄4 19.46, df 1⁄4 2, p<.0001. Effects of diagnoses on neuropsychological test performance were identified for tests assessing abstract thinking, memory, attention, verbal fluency, visuo-spatial thinking, and mental flexibility. However, interactions between cognitive diagnoses and cohort (C 30/C 50) were restricted to a test assessing abstract thinking abilities. Conclusions:Findings from this prospective study of non-clinical samples aged about 65 years support our hypothesis of a decreasing prevalence of MCI in a later born 1950-52 cohort compared with an earlier born 1930-32 cohort. We propose that cognitive reserve was increased in the later-born cohort possibly because school education was significantly longer in the laterthan the earlier-born cohort. Additional factors (I.e. better control of hypertension or hypercholesterimia) may also be relevant because better neuropsychological test performance in the later-born remained after adjustment for school education. With the exception of abstract thinking test performance, the profile of age-related neuropsychological deficits was similar between cohorts suggesting that abstract thinking contributes exquisitely to cognitive reserve.