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[P3–290]: RELATIONSHIP BETWEEN SLEEP DISTURBANCE AND COGNITIVE DYSFUNCTION IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT
Author(s) -
Shin Ilseon,
Lim Chanyoung,
Shin Heeyoung,
Kim JaeMin,
Kim SungWan,
Yoon JinSang
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1504
Subject(s) - sleep disorder , psychology , cognition , disturbance (geology) , depression (economics) , neuropsychological test , sleep (system call) , neuropsychology , effects of sleep deprivation on cognitive performance , audiology , clinical psychology , psychiatry , medicine , paleontology , macroeconomics , computer science , economics , biology , operating system
(orientation, attention, language-comprehension, languagerepetition, language-naming, construction, memory, calculation, similarity and judgement). Each of subtests assesses different cognitive domains. Specific binding ratio (SBR) of the FP-CIT SPECT was compared with each score of 10 subtests. Results:Among the 10 separate subtests, scores of similarity and judgement, both of them examine frontal-executive function, correlated with the SBR. Conclusions: Abilities for similarity and judgement may be commanded by dopaminergic front-striatal circuit and may have a common mechanism with motor function in PD patients.