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[P3–273]: EFFECTS OF RISPERIDONE AND GALANTAMINE TREATMENT ON ALZHEIMER BIOMARKER LEVELS IN CEREBROSPINAL FLUID
Author(s) -
Bloniecki Victor,
FreundLevi Yvonne,
Blennow Kaj,
Aarsland Dag,
Cummings Jeffrey L.,
Winblad Bengt
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1487
Subject(s) - irritability , risperidone , medicine , biomarker , cerebrospinal fluid , galantamine , dementia , gastroenterology , psychiatry , disease , schizophrenia (object oriented programming) , donepezil , menopause , biochemistry , chemistry
showed a specific absence of spatiotemporal and perceptual features in the narratives they produced. These deficits in autobiographical memory occurred alongside visuospatial and global visual imagery deficits. Voxel-basedmorphometry confirmed prominent prominent atrophy of the parietal and occipital cortices, but sparing of the hippocampi bilaterally. Conclusions: Our findings present novel evidence for remote memory impairment in PCA.We propose that damage to posterior regions of the brain disrupts access to visual information integral to the autobiographical memory trace.