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[P2–571]: EXERCISE TRAINING AND CEREBRAL BLOOD FLOW IN PRECLINICAL ALZHEIMER's DISEASE: RESULTS FROM THE AEROBIC EXERCISE AND COGNITIVE HEALTH (REACH) STUDY
Author(s) -
Dougherty Ryan J.,
Boots Elizabeth A.,
Rowley Howard A.,
Hermann Bruce P.,
Sager Mark A.,
Johnson Sterling C.,
Edwards Dorothy Farrar,
Cook Dane B.,
Okonkwo Ozioma C.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1230
Subject(s) - cardiorespiratory fitness , cerebral blood flow , medicine , aerobic exercise , quartile , physical therapy , analysis of variance , brain aging , repeated measures design , disease , cardiology , physical medicine and rehabilitation , confidence interval , statistics , mathematics
Cognition, z scores Global cognitive function .55 (.42 to .66) .48 (.37 to .6) .07 (–.11 to .22) .509 Executive function .33 (.13 to .52) .34 (.17 to .52) –.01 (–.28 to .24) .882 Processing speed .32 (.15 to .5) .19 (.03 to .35) .13 (–.1 to .37) .581 Memory .97 (.72 to 1.23) .88 (.64 to 1.1) .09 (–.25 to .44) .267 Verbal fluency .52 (.31 to .73) .55 (.36 to .75) –.13 (–.56 to 29) .822 Mobility Usual gait velocity, cm/s 1.77 (–3 to 6.6) 9.36 (4.94 to 13.78) –7.58 (–14.12 to –1.03) .024* Usual step length, cm .35 (–1.2 to 1.9) 3.36 (1.95 to 4.77) –3.01 ( – 5.10 to –.91) 006* Usual gait variability, CoV, % –.67 (–1.8 to .45) –.24 (–1.2 to .75) –.42 (–1.93 to 1.07) .574 DT gait velocity, cm/s 7.69 (1.5 to 13.9) 11.1 (5.4 to 16.7) –3.37 (–11.76 to 5) .424 DT step length, cm 2.11 (–.11 to 4.33) 3.81 (1.77 to 5.84) –1.69 (–4.71 to 1.31) .264 DT gait variability, CoV, % – 2.97 ( – 5.64 to .31) –.5 (–2.91 to 1.91) –2.47 (–6.07 to 1.12) .175