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[P2–465]: COMPARISON BETWEEN THE MINI‐MENTAL STATE EXAMINATION AND THE MINI‐MENTAL STATE EXAMINATION‐2 IN KOREAN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND ALZHEIMER's DISEASE
Author(s) -
Baek Min Jae,
Kim Karyeong,
Park Young Ho,
Chang YoungHee,
Wang Minjung,
Kim SangYun
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1122
Subject(s) - mini–mental state examination , discriminant validity , cognitive impairment , receiver operating characteristic , medicine , neuropsychology , linear discriminant analysis , psychology , cognition , psychiatry , disease , clinical psychology , psychometrics , artificial intelligence , internal consistency , computer science
over time. Even among those (n1⁄4282) we have previously identified as ‘false positive’ MCI diagnostic errors in ADNI (Edmonds et al., 2015), only 15 of the 24 ADNI reverters were baseline ‘false positives’, thereby missing 94.7% of participants in whom a cognitively normal diagnosis appears better justified based on neuropsychological performance, normal biomarkers, lack of cortical thinning, and low progression rates. Additionally, compared to ADNI, the NP criteria identified more new MCI cases and greater CSF reductions in b-amyloid in normal-to-MCI individuals, consistent with their cognitive decline. We conclude that ADNI has an artificially low reversion rate (3%) even when compared to metaanalytic reversion rates (24%) based largely on conventional criteria (Malek-Ahmadi, 2016).