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[P2–460]: IS THE CAMBRIDGE COGNITIVE TEST (CAMCOG) A USEFUL TOOL TO PREDICT THE PATHOLOGICAL STATUS OF CEREBROSPINAL FLUID IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI)?
Author(s) -
Pais Marcos Vasconcelos,
Stella Florindo,
Radanovic Marcia,
Loureiro Júlia Cunha,
Canineu Paulo Renato,
Valiengo Leandro L.C.,
Forlenza Orestes Vicente
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.1117
Subject(s) - dementia , cognition , neuropsychology , psychology , cognitive impairment , pathological , cognitive decline , medicine , clinical psychology , psychiatry , disease
(typing) a text based upon presented images. A randomised set of 50 validated images was created for this purpose; the images belonging to two categories: living & non-living. Firstly, the participants (n1⁄440 healthy elderly) performed a typing task, which provided information about the typing speed of each individual. Secondly, two narrative writing tasks were carried out, one simple and one complex. The data were collected with the keystroke logging program Inputlog, which logs and time stamps keystroke activity to reconstruct and describe text production processes. The data were analysed using a selection of writing process and product variables, such as general writing process measures, detailed pause analysis, linguistic analysis and text length. The intrapersonal interkey transition times from the typing task were taken into account as a covariate. Results:The texts from the narrative tasks were significantly longer compared to previous studies, providing sufficient text and process data for analyses. The healthy elderly did take significantly more time to produce the complex than the simple text. Nevertheless, the number of words per minute remained comparable between simple and complex. The pauses within and before words varied, even when taking personal typing abilities (obtained by the typing task) into account. Conclusions:Neuropsychological language test can be used to characterise cognitive decline upon aging. Previous studies have already revealed that there are difference between DAT patients and cognitive healthy elderly on a number of key variables. Since the healthy elderly had no difficulty producing a text of significant length, the narrative writing tasks can be used for process analyses to compare cognitive decline in healthy aging and Alzheimer’s disease.