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P1‐026: NIH Toolbox‐Cognitive and Cogstate Computer‐Based Assessment in the Identification of MCI Subtypes
Author(s) -
Garcia Sarah,
Kavcic Voyko,
Shair Sarah,
Lichtenberg Peter,
Paulson Henry L.,
Davis Kacy,
Overall Janet,
Rose Edna,
Campbell Stephen,
Teboe Sherry,
Bhaumik Arijit,
Hampstead Benjamin,
Dodge Hiroko H.,
Giordani Bruno
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.773
Subject(s) - medicine , neuropsychology , cognition , cohort , cognitive impairment , gerontology , population , audiology , psychology , clinical psychology , psychiatry , environmental health
nucleus (Figure 1). Conclusions: CBF decreased as individuals approached the expected age of disease onset and this CBF decrease was accelerated in the presymptomatic mutation carriers compared to controls, in key regions implicated in FTD. These preliminary findings demonstrate the potential utility of non-invasive perfusion MRI as an early biomarker for genetic FTD. References 1. Montine et al., Neurology 2014 2. Rohrer et al., Lancet Neurol 2015