Premium
P4‐212: Predicting Progression From Mild Cognitive Impairment (MCI) to Alzheimer’s Disease Using Perfusion Brain Spect Imaging Analysis of The Initial Hospital Visit
Author(s) -
Nakata Ruka,
Yuasa Takayuki,
Nakao Yoko,
Ichinose Katsuhiro,
Tomita Itsuro,
Satoh Hideyo,
Satoh Akira,
Ochi Makoto,
Seto Makiko,
Mitsuhiro Tsujihata
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.2304
Subject(s) - precuneus , angular gyrus , spect imaging , medicine , perfusion scanning , inferior parietal lobule , superior parietal lobule , supramarginal gyrus , cardiology , perfusion , psychology , nuclear medicine , radiology , cognition , psychiatry , functional magnetic resonance imaging
[.58,.61,.06] outperforms the other three models: LR [.53,.51,.07], SVM: [.54,.55,.08], and RF:[.52,.54,.10]. Significant improvement is seen with HC modality with NN model compared to baseline models. All four model classes show boost in performance when HC and CT modalities are combined. Conclusions:The correlation scores validate the utility of NN as prediction model. The proposed modular architecture of the NN provides a framework for multimodal analysis, and can be extended to incorporate other data modalities and/or predicting other clinical scales.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom