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P4‐128: Low Prevalence of Amyloid Positivity in Healthy Elderly Participants of a Methodology Study Evaluating Remote Tablet‐Based Cognitive Learning
Author(s) -
Leurent Claire,
Goodman James,
Pickering Eve H.,
He Ping,
Duvvuri Sridhar,
Martucci Eddie,
Kellogg Scott,
Purcell Derek,
Barakos Jerome,
Klein Gregory,
Kupiec James,
Alexander Robert C.
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.2219
Subject(s) - cognition , amyloid (mycology) , medicine , psychology , placebo , effects of sleep deprivation on cognitive performance , audiology , pathology , psychiatry , alternative medicine
Conclusions Though a gold standard of amyloid burden was not available, results indicate that a hybrid qualitative visual / quantitative method can be used to obtain greater concordance between quantitative and visual results. Clinical studies using only visual or only SUVR information for eligibility decisions must understand the implications of potential differences between the visual and quantitative methodologies.