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P3‐188: Performance Testing and Analytical Validation of New Elisas for B‐Amyloid Isoforms (AB(1‐38), AB(1‐40), AB(1‐42)) in Plasma
Author(s) -
Herbst Victor,
Zeplin Katharina,
Mauroo Kimberley,
Demeyer Leentje,
Vanderstichele Hugo Marcel,
Stoops Erik
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.1848
Subject(s) - medicine , analyte , chromatography , predictive value , oncology , chemistry
cortisol who reported any alcohol consumption (p<0.0001, Synergy Index (SI): 11.6 (95%CI: 6.4-16.9)). Reducing the sample to only those who consistently consumed wine (N1⁄4293) compared with those reporting no alcohol consumption (N1⁄4224), we saw the effect increase, with those with high cortisol who reported no alcohol consumption 9.4 times more likely to develop AD compared with those with low cortisol who reported any alcohol consumption (p<0.0001, SI: 9.5 (2.9-15.9)). Conclusions: These findings demonstrate the benefit of regular moderate consumption of alcohol to combat the increased risk of AD due to the stress hormone cortisol.