P3‐188: Performance Testing and Analytical Validation of New Elisas for B‐Amyloid Isoforms (AB(1‐38), AB(1‐40), AB(1‐42)) in Plasma

cortisol who reported any alcohol consumption (p<0.0001, Synergy Index (SI): 11.6 (95%CI: 6.4-16.9)). Reducing the sample to only those who consistently consumed wine (N1⁄4293) compared with those reporting no alcohol consumption (N1⁄4224), we saw the effect increase, with those with high cortisol who reported no alcohol consumption 9.4 times more likely to develop AD compared with those with low cortisol who reported any alcohol consumption (p<0.0001, SI: 9.5 (2.9-15.9)). Conclusions: These findings demonstrate the benefit of regular moderate consumption of alcohol to combat the increased risk of AD due to the stress hormone cortisol.