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IC‐P‐138: High CSF TAU is Related to Reduced Hippocampal Volume and Subjective Cognitive Decline in Healthy Elderly With Amyloid Pathology
Author(s) -
Binette Alexa Pichet,
Vogel Jacob W.,
Fonov Vladimir S.,
Madjar Cécile,
Tremblay-Mercier Jennifer,
Breitner John C.S.,
Collins Louis,
Poirier Judes,
Villeneuve Sylvia
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.168
Subject(s) - cerebrospinal fluid , medicine , apolipoprotein e , hippocampal formation , cohort , pathology , dementia , psychology , alzheimer's disease , oncology , disease
tion and calcification were more frequently seen in the clinical samples (p<0.05), which were sensitively detected using T2*GRE. Conclusions:BALI was successfully applied to several routine clinical MRI sequences for the evaluation of whole brain structural health in aging and dementia. The T1WI and T2WI based evaluation appeared to consistently capture common brain changes in the various BALI categories. Inclusion of T2-FLAIR and T2*GRE may increase BALI sensitivity.